Voluntary movement dysfunction in schizophrenics

P. Bart Vrtunski*, Dale M. Simpson, Herbert Y. Meltzer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Several aspects of fine motor control were compared in schizophrenics and two control populations. The motor behavior analyzed was a button-press response in a forced choice paradigm. Three areas of abnormality were seen in schizophrenics: first, the interval preceding the motor response was characterized by reduced motor steadiness prior to the button-press response; second, the motor response was made with excessive force (hyperdynamia); and third, the agonist-antagonist synchrony (motor reversal) was impaired. Schizophrenics on and off neuroleptics did not differ on any measure of motor control, but schizophrenics with clinically observed tardive dyskinesia were found to have significantly less steadiness prior to the motor response than other schizophrenics.

Original languageEnglish (US)
Pages (from-to)529-539
Number of pages11
JournalBiological psychiatry
Issue number5
StatePublished - Mar 1 1989

ASJC Scopus subject areas

  • Biological Psychiatry


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