Waterproof, electronics-enabled, epidermal microfluidic devices for sweat collection, biomarker analysis, and thermography in aquatic settings

Jonathan T. Reeder, Jungil Choi, Yeguang Xue, Philipp Gutruf, Justin Hanson, Mark Liu, Tyler Ray, Amay J. Bandodkar, Raudel Avila, Wei Xia, Siddharth Krishnan, Shuai Xu, Kelly Barnes, Matthew Pahnke, Roozbeh Ghaffari, Yonggang Huang, John A Rogers*

*Corresponding author for this work

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Noninvasive, in situ biochemical monitoring of physiological status, via the use of sweat, could enable new forms of health care diagnostics and personalized hydration strategies. Recent advances in sweat collection and sensing technologies offer powerful capabilities, but they are not effective for use in extreme situations such as aquatic or arid environments, because of unique challenges in eliminating interference/contamination from surrounding water, maintaining robust adhesion in the presence of viscous drag forces and/or vigorous motion, and preventing evaporation of collected sweat. This paper introduces materials and designs for waterproof, epidermal, microfluidic and electronic systems that adhere to the skin to enable capture, storage, and analysis of sweat, even while fully underwater. Field trials demonstrate the ability of these devices to collect quantitative in situ measurements of local sweat chloride concentration, local sweat loss (and sweat rate), and skin temperature during vigorous physical activity in controlled, indoor conditions and in open-ocean swimming.

Original languageEnglish (US)
Article numbereaau6356
JournalScience Advances
Volume5
Issue number1
DOIs
StatePublished - Jan 25 2019

Fingerprint

sweat
biomarkers
microfluidic devices
electronics
viscous drag
in situ measurement
health
hydration
oceans
contamination
adhesion
chlorides
evaporation
interference

ASJC Scopus subject areas

  • General
  • Physics and Astronomy (miscellaneous)

Cite this

Reeder, Jonathan T. ; Choi, Jungil ; Xue, Yeguang ; Gutruf, Philipp ; Hanson, Justin ; Liu, Mark ; Ray, Tyler ; Bandodkar, Amay J. ; Avila, Raudel ; Xia, Wei ; Krishnan, Siddharth ; Xu, Shuai ; Barnes, Kelly ; Pahnke, Matthew ; Ghaffari, Roozbeh ; Huang, Yonggang ; Rogers, John A. / Waterproof, electronics-enabled, epidermal microfluidic devices for sweat collection, biomarker analysis, and thermography in aquatic settings. In: Science Advances. 2019 ; Vol. 5, No. 1.
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abstract = "Noninvasive, in situ biochemical monitoring of physiological status, via the use of sweat, could enable new forms of health care diagnostics and personalized hydration strategies. Recent advances in sweat collection and sensing technologies offer powerful capabilities, but they are not effective for use in extreme situations such as aquatic or arid environments, because of unique challenges in eliminating interference/contamination from surrounding water, maintaining robust adhesion in the presence of viscous drag forces and/or vigorous motion, and preventing evaporation of collected sweat. This paper introduces materials and designs for waterproof, epidermal, microfluidic and electronic systems that adhere to the skin to enable capture, storage, and analysis of sweat, even while fully underwater. Field trials demonstrate the ability of these devices to collect quantitative in situ measurements of local sweat chloride concentration, local sweat loss (and sweat rate), and skin temperature during vigorous physical activity in controlled, indoor conditions and in open-ocean swimming.",
author = "Reeder, {Jonathan T.} and Jungil Choi and Yeguang Xue and Philipp Gutruf and Justin Hanson and Mark Liu and Tyler Ray and Bandodkar, {Amay J.} and Raudel Avila and Wei Xia and Siddharth Krishnan and Shuai Xu and Kelly Barnes and Matthew Pahnke and Roozbeh Ghaffari and Yonggang Huang and Rogers, {John A}",
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Reeder, JT, Choi, J, Xue, Y, Gutruf, P, Hanson, J, Liu, M, Ray, T, Bandodkar, AJ, Avila, R, Xia, W, Krishnan, S, Xu, S, Barnes, K, Pahnke, M, Ghaffari, R, Huang, Y & Rogers, JA 2019, 'Waterproof, electronics-enabled, epidermal microfluidic devices for sweat collection, biomarker analysis, and thermography in aquatic settings', Science Advances, vol. 5, no. 1, eaau6356. https://doi.org/10.1126/sciadv.aau6356

Waterproof, electronics-enabled, epidermal microfluidic devices for sweat collection, biomarker analysis, and thermography in aquatic settings. / Reeder, Jonathan T.; Choi, Jungil; Xue, Yeguang; Gutruf, Philipp; Hanson, Justin; Liu, Mark; Ray, Tyler; Bandodkar, Amay J.; Avila, Raudel; Xia, Wei; Krishnan, Siddharth; Xu, Shuai; Barnes, Kelly; Pahnke, Matthew; Ghaffari, Roozbeh; Huang, Yonggang; Rogers, John A.

In: Science Advances, Vol. 5, No. 1, eaau6356, 25.01.2019.

Research output: Contribution to journalArticle

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AU - Choi, Jungil

AU - Xue, Yeguang

AU - Gutruf, Philipp

AU - Hanson, Justin

AU - Liu, Mark

AU - Ray, Tyler

AU - Bandodkar, Amay J.

AU - Avila, Raudel

AU - Xia, Wei

AU - Krishnan, Siddharth

AU - Xu, Shuai

AU - Barnes, Kelly

AU - Pahnke, Matthew

AU - Ghaffari, Roozbeh

AU - Huang, Yonggang

AU - Rogers, John A

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AB - Noninvasive, in situ biochemical monitoring of physiological status, via the use of sweat, could enable new forms of health care diagnostics and personalized hydration strategies. Recent advances in sweat collection and sensing technologies offer powerful capabilities, but they are not effective for use in extreme situations such as aquatic or arid environments, because of unique challenges in eliminating interference/contamination from surrounding water, maintaining robust adhesion in the presence of viscous drag forces and/or vigorous motion, and preventing evaporation of collected sweat. This paper introduces materials and designs for waterproof, epidermal, microfluidic and electronic systems that adhere to the skin to enable capture, storage, and analysis of sweat, even while fully underwater. Field trials demonstrate the ability of these devices to collect quantitative in situ measurements of local sweat chloride concentration, local sweat loss (and sweat rate), and skin temperature during vigorous physical activity in controlled, indoor conditions and in open-ocean swimming.

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