Weight Loss Strategies for Treatment of Obesity: Lifestyle Management and Pharmacotherapy

Robert F. Kushner*

*Corresponding author for this work

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Obesity is one of the most serious and prevalent non-communicable diseases of the twenty-first century. It is also a patient-centered condition in which affected individuals seek treatment through a variety of commercial, medical and surgical approaches. Considering obesity as a chronic medical disease state helps to frame the concept of using a three-stepped intensification of care approach to weight management. As a foundation, all patients should be counseled on evidence-based lifestyle approaches that include diet, physical activity and behavior change therapies. At the second tier, four new pharmacological agents, lorcaserin, phentermine/topiramate, naltrexone/bupropion and liraglutide have been approved since 2012 as adjuncts to lifestyle modification. The third step, bariatric surgery, has been demonstrated to be the most effective and long-term treatment for individuals with severe obesity or moderate obesity complicated by co-morbid conditions that is not responsive to non-surgical approaches. By using a medical model, clinicians can provide more proactive and effective treatments in assisting their patients with weight loss.

Original languageEnglish (US)
Pages (from-to)246-252
Number of pages7
JournalProgress in Cardiovascular Diseases
Volume61
Issue number2
DOIs
StatePublished - Jul 1 2018

Keywords

  • Diet
  • Lifestyle
  • Obesity
  • Pharmacology

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Weight Loss Strategies for Treatment of Obesity: Lifestyle Management and Pharmacotherapy'. Together they form a unique fingerprint.

  • Cite this