What can surface chemistry do for cell biology?

Milan Mrksich*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

151 Scopus citations


Recent research has enhanced the development of substrates that serve as models of extracellular matrix and their use in studies of cell adhesion and migration. Advances include the development of methods to prepare substrates having ligands immobilized in controlled densities and patterns, and recent work that is developing dynamic substrates which can modulate, in real-time, the activities of ligands. These technologies are providing new opportunities for studies of cell-extracellular-matrix interactions.

Original languageEnglish (US)
Pages (from-to)794-797
Number of pages4
JournalCurrent Opinion in Chemical Biology
Issue number6
StatePublished - Dec 1 2002

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry


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