What every neuropathologist needs to know: Update on cIMPACT-NOW

Gabrielle A. Yeaney; Daniel J. Brat

doi:10.1093/jnen/nlz012

What every neuropathologist needs to know: Update on cIMPACT-NOW

Gabrielle A. Yeaney, Daniel J. Brat^*

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

World Health Organization (WHO) central nervous system tumor classification represents the primary source of updates on diagnostic classes, grades, and criteria. However, recent and ongoing advances in molecular pathogenesis warrant more rapid integration into clinical practice between WHO updates. To accomplish this, the consortium to inform molecular and practical approaches to CNS tumor taxonomy-not official WHO (cIMPACT-NOW) was established in 2016. Since then, cIMPACT-NOW has convened 3 separate working committees to address classification and grading questions and challenges. This review covers the progress that these working committees have made on their specific topics.

Original language	English (US)
Pages (from-to)	294-296
Number of pages	3
Journal	Journal of neuropathology and experimental neurology
Volume	78
Issue number	4
DOIs	https://doi.org/10.1093/jnen/nlz012
State	Published - Apr 1 2019

Keywords

Brain tumor
CNS neoplasm
Consortium
Molecular
Taxonomy
WHO classification
cIMPACT

ASJC Scopus subject areas

Pathology and Forensic Medicine
Neurology
Clinical Neurology
Cellular and Molecular Neuroscience

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10.1093/jnen/nlz012

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title = "What every neuropathologist needs to know: Update on cIMPACT-NOW",

abstract = "World Health Organization (WHO) central nervous system tumor classification represents the primary source of updates on diagnostic classes, grades, and criteria. However, recent and ongoing advances in molecular pathogenesis warrant more rapid integration into clinical practice between WHO updates. To accomplish this, the consortium to inform molecular and practical approaches to CNS tumor taxonomy-not official WHO (cIMPACT-NOW) was established in 2016. Since then, cIMPACT-NOW has convened 3 separate working committees to address classification and grading questions and challenges. This review covers the progress that these working committees have made on their specific topics.",

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AB - World Health Organization (WHO) central nervous system tumor classification represents the primary source of updates on diagnostic classes, grades, and criteria. However, recent and ongoing advances in molecular pathogenesis warrant more rapid integration into clinical practice between WHO updates. To accomplish this, the consortium to inform molecular and practical approaches to CNS tumor taxonomy-not official WHO (cIMPACT-NOW) was established in 2016. Since then, cIMPACT-NOW has convened 3 separate working committees to address classification and grading questions and challenges. This review covers the progress that these working committees have made on their specific topics.

KW - Brain tumor

KW - CNS neoplasm

KW - Consortium

KW - Molecular

KW - Taxonomy

KW - WHO classification

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JO - Journal of Neuropathology and Experimental Neurology

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ER -

What every neuropathologist needs to know: Update on cIMPACT-NOW

Abstract

Keywords

ASJC Scopus subject areas

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