What is the evidence for using hydroxyurea for secondary stroke prevention?

Jeffrey D. Lebensburger*, Michael R. DeBaun, Alexis A. Thompson

*Corresponding author for this work

Research output: Contribution to journalReview article

1 Scopus citations


A 10-year-old male patient with hemoglobin SS suffered a stroke at 7 years of age and was initially transfused at the time of presentation to lower the hemoglobin S concentration to < 30%. You are asked by the family if their child can be treated with oral hydroxyurea rather than monthly transfusions for the secondary prevention of strokes.


ASJC Scopus subject areas

  • Hematology

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