What progress have we made in managing inflammatory breast cancer?

Shaheenah Dawood, Susan G. Komen, Massimo Cristofanilli*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Inflammatory breast cancer (IBC) is a rare and aggressive form of the disease. It is diagnosed based on clinical signs of a rapidly enlarging, tender, erythematous, edematous breast that often presents without an underlying breast mass. IBC historically was considered a uniformly fatal disease. With the advent of multimodality treatments including primary systemic chemotherapy, surgery, and radiation therapy, approximately one-third of women diagnosed with IBC will become long-term survivors. This review examines the limitations of the current definition of IBC, explores our current understanding of the biology of IBC, and reviews the many exciting advances in locoregional and systemic treatment of IBC.

Original languageEnglish (US)
Pages (from-to)673-679
Number of pages7
JournalONCOLOGY
Volume21
Issue number6
StatePublished - May 1 2007

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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