Wireless, Battery-Free Epidermal Electronics for Continuous, Quantitative, Multimodal Thermal Characterization of Skin

Siddharth R. Krishnan, Chun Ju Su, Zhaoqian Xie, Manish Patel, Surabhi R. Madhvapathy, Yeshou Xu, Juliet Freudman, Barry Ng, Seung Yun Heo, Heling Wang, Tyler R. Ray, John Leshock, Izabela Stankiewicz, Xue Feng, Yonggang Huang, Philipp Gutruf*, John A Rogers

*Corresponding author for this work

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Precise, quantitative measurements of the thermal properties of human skin can yield insights into thermoregulatory function, hydration, blood perfusion, wound healing, and other parameters of clinical interest. The need for wired power supply systems and data communication hardware limits, however, practical applicability of existing devices designed for measurements of this type. Here, a set of advanced materials, mechanics designs, integration schemes, and wireless circuits is reported as the basis for wireless, battery-free sensors that softly interface to the skin to enable precise measurements of its temperature and thermal transport properties. Calibration processes connect these parameters to the hydration state of the skin, the dynamics of near-surface flow through blood vessels and implanted catheters, and to recovery processes following trauma. Systematic engineering studies yield quantitative metrics in precision and reliability in real-world conditions. Evaluations on five human subjects demonstrate the capabilities in measurements of skin hydration and injury, including examples of continuous wear and monitoring over a period of 1 week, without disrupting natural daily activities.

Original languageEnglish (US)
Article number1803192
JournalSmall
Volume14
Issue number47
DOIs
StatePublished - Nov 22 2018

Fingerprint

Skin
Electronic equipment
Hot Temperature
Hydration
Electric Power Supplies
Catheters
Wounds and Injuries
Blood vessels
Electric power systems
Mechanics
Information Systems
Wound Healing
Transport properties
Calibration
Blood Vessels
Blood
Thermodynamic properties
Perfusion
Communication
Wear of materials

Keywords

  • NFC
  • epidermal electronics
  • hydration
  • thermal sensing
  • wireless electronics

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)
  • Engineering (miscellaneous)

Cite this

Krishnan, Siddharth R. ; Su, Chun Ju ; Xie, Zhaoqian ; Patel, Manish ; Madhvapathy, Surabhi R. ; Xu, Yeshou ; Freudman, Juliet ; Ng, Barry ; Heo, Seung Yun ; Wang, Heling ; Ray, Tyler R. ; Leshock, John ; Stankiewicz, Izabela ; Feng, Xue ; Huang, Yonggang ; Gutruf, Philipp ; Rogers, John A. / Wireless, Battery-Free Epidermal Electronics for Continuous, Quantitative, Multimodal Thermal Characterization of Skin. In: Small. 2018 ; Vol. 14, No. 47.
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abstract = "Precise, quantitative measurements of the thermal properties of human skin can yield insights into thermoregulatory function, hydration, blood perfusion, wound healing, and other parameters of clinical interest. The need for wired power supply systems and data communication hardware limits, however, practical applicability of existing devices designed for measurements of this type. Here, a set of advanced materials, mechanics designs, integration schemes, and wireless circuits is reported as the basis for wireless, battery-free sensors that softly interface to the skin to enable precise measurements of its temperature and thermal transport properties. Calibration processes connect these parameters to the hydration state of the skin, the dynamics of near-surface flow through blood vessels and implanted catheters, and to recovery processes following trauma. Systematic engineering studies yield quantitative metrics in precision and reliability in real-world conditions. Evaluations on five human subjects demonstrate the capabilities in measurements of skin hydration and injury, including examples of continuous wear and monitoring over a period of 1 week, without disrupting natural daily activities.",
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author = "Krishnan, {Siddharth R.} and Su, {Chun Ju} and Zhaoqian Xie and Manish Patel and Madhvapathy, {Surabhi R.} and Yeshou Xu and Juliet Freudman and Barry Ng and Heo, {Seung Yun} and Heling Wang and Ray, {Tyler R.} and John Leshock and Izabela Stankiewicz and Xue Feng and Yonggang Huang and Philipp Gutruf and Rogers, {John A}",
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Krishnan, SR, Su, CJ, Xie, Z, Patel, M, Madhvapathy, SR, Xu, Y, Freudman, J, Ng, B, Heo, SY, Wang, H, Ray, TR, Leshock, J, Stankiewicz, I, Feng, X, Huang, Y, Gutruf, P & Rogers, JA 2018, 'Wireless, Battery-Free Epidermal Electronics for Continuous, Quantitative, Multimodal Thermal Characterization of Skin', Small, vol. 14, no. 47, 1803192. https://doi.org/10.1002/smll.201803192

Wireless, Battery-Free Epidermal Electronics for Continuous, Quantitative, Multimodal Thermal Characterization of Skin. / Krishnan, Siddharth R.; Su, Chun Ju; Xie, Zhaoqian; Patel, Manish; Madhvapathy, Surabhi R.; Xu, Yeshou; Freudman, Juliet; Ng, Barry; Heo, Seung Yun; Wang, Heling; Ray, Tyler R.; Leshock, John; Stankiewicz, Izabela; Feng, Xue; Huang, Yonggang; Gutruf, Philipp; Rogers, John A.

In: Small, Vol. 14, No. 47, 1803192, 22.11.2018.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Wireless, Battery-Free Epidermal Electronics for Continuous, Quantitative, Multimodal Thermal Characterization of Skin

AU - Krishnan, Siddharth R.

AU - Su, Chun Ju

AU - Xie, Zhaoqian

AU - Patel, Manish

AU - Madhvapathy, Surabhi R.

AU - Xu, Yeshou

AU - Freudman, Juliet

AU - Ng, Barry

AU - Heo, Seung Yun

AU - Wang, Heling

AU - Ray, Tyler R.

AU - Leshock, John

AU - Stankiewicz, Izabela

AU - Feng, Xue

AU - Huang, Yonggang

AU - Gutruf, Philipp

AU - Rogers, John A

PY - 2018/11/22

Y1 - 2018/11/22

N2 - Precise, quantitative measurements of the thermal properties of human skin can yield insights into thermoregulatory function, hydration, blood perfusion, wound healing, and other parameters of clinical interest. The need for wired power supply systems and data communication hardware limits, however, practical applicability of existing devices designed for measurements of this type. Here, a set of advanced materials, mechanics designs, integration schemes, and wireless circuits is reported as the basis for wireless, battery-free sensors that softly interface to the skin to enable precise measurements of its temperature and thermal transport properties. Calibration processes connect these parameters to the hydration state of the skin, the dynamics of near-surface flow through blood vessels and implanted catheters, and to recovery processes following trauma. Systematic engineering studies yield quantitative metrics in precision and reliability in real-world conditions. Evaluations on five human subjects demonstrate the capabilities in measurements of skin hydration and injury, including examples of continuous wear and monitoring over a period of 1 week, without disrupting natural daily activities.

AB - Precise, quantitative measurements of the thermal properties of human skin can yield insights into thermoregulatory function, hydration, blood perfusion, wound healing, and other parameters of clinical interest. The need for wired power supply systems and data communication hardware limits, however, practical applicability of existing devices designed for measurements of this type. Here, a set of advanced materials, mechanics designs, integration schemes, and wireless circuits is reported as the basis for wireless, battery-free sensors that softly interface to the skin to enable precise measurements of its temperature and thermal transport properties. Calibration processes connect these parameters to the hydration state of the skin, the dynamics of near-surface flow through blood vessels and implanted catheters, and to recovery processes following trauma. Systematic engineering studies yield quantitative metrics in precision and reliability in real-world conditions. Evaluations on five human subjects demonstrate the capabilities in measurements of skin hydration and injury, including examples of continuous wear and monitoring over a period of 1 week, without disrupting natural daily activities.

KW - NFC

KW - epidermal electronics

KW - hydration

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KW - wireless electronics

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