Wireless broadband acousto-mechanical sensing system for continuous physiological monitoring

Jae Young Yoo, Seyong Oh, Wissam Shalish, Woo Youl Maeng, Emily Cerier, Emily Jeanne, Myung Kun Chung, Shasha Lv, Yunyun Wu, Seonggwang Yoo, Andreas Tzavelis, Jacob Trueb, Minsu Park, Hyoyoung Jeong, Efe Okunzuwa, Slobodanka Smilkova, Gyeongwu Kim, Junha Kim, Gooyoon Chung, Yoonseok ParkAnthony Banks, Shuai Xu, Guilherme M. Sant’Anna, Debra E. Weese-Mayer, Ankit Bharat*, John A. Rogers*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The human body generates various forms of subtle, broadband acousto-mechanical signals that contain information on cardiorespiratory and gastrointestinal health with potential application for continuous physiological monitoring. Existing device options, ranging from digital stethoscopes to inertial measurement units, offer useful capabilities but have disadvantages such as restricted measurement locations that prevent continuous, longitudinal tracking and that constrain their use to controlled environments. Here we present a wireless, broadband acousto-mechanical sensing network that circumvents these limitations and provides information on processes including slow movements within the body, digestive activity, respiratory sounds and cardiac cycles, all with clinical grade accuracy and independent of artifacts from ambient sounds. This system can also perform spatiotemporal mapping of the dynamics of gastrointestinal processes and airflow into and out of the lungs. To demonstrate the capabilities of this system we used it to monitor constrained respiratory airflow and intestinal motility in neonates in the neonatal intensive care unit (n = 15), and to assess regional lung function in patients undergoing thoracic surgery (n = 55). This broadband acousto-mechanical sensing system holds the potential to help mitigate cardiorespiratory instability and manage disease progression in patients through continuous monitoring of physiological signals, in both the clinical and nonclinical setting.

Original languageEnglish (US)
Pages (from-to)3137-3148
Number of pages12
JournalNature Medicine
Issue number12
StatePublished - Dec 2023

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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