Wireless, Soft Sensors of Skin Hydration with Designs Optimized for Rapid, Accurate Diagnostics of Dermatological Health

Jaeho Shin, Heling Wang, Kyeongha Kwon, Diana Ostojich, Zach Christiansen, Jaime Berkovich, Yoonseok Park, Zhengwei Li, Geumbee Lee, Rania Nasif, Ted S. Chung, Chun Ju Su, Jaeman Lim, Hitoki Kubota, Akihiko Ikoma, Yi An Lu, Derrick H. Lin, Shuai Xu, Anthony Banks, Jan Kai ChangJohn A. Rogers*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Accurate measurements of skin hydration are of great interest to dermatological science and clinical practice. This parameter serves as a relevant surrogate of skin barrier function, a key representative benchmark for overall skin health. The skin hydration sensor (SHS) is a soft, skin-interfaced wireless system that exploits a thermal measurement method, as an alternative to conventional impedance-based hand-held probes. This study presents multiple strategies for maximizing the sensitivity and reliability of this previously reported SHS platform. An in-depth analysis of the thermal physics of the measurement process serves as the basis for structural optimizations of the electronics and the interface to the skin. Additional engineering advances eliminate variabilities associated with manual use of the device and with protocols for the measurement. The cumulative effect is an improvement in sensitivity by 135% and in repeatability by 36% over previously reported results. Pilot trials on more than 200 patients in a dermatology clinic validate the practical utility of the sensor for fast, reliable measurements.

Original languageEnglish (US)
Article number2202021
JournalAdvanced Healthcare Materials
Volume12
Issue number4
DOIs
StatePublished - Feb 6 2023

Keywords

  • biomedical devices
  • diagnostics
  • flexible electronics
  • health monitoring
  • wireless electronics

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Pharmaceutical Science

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