Wnt signaling: A shaggy dogma tale

Elizabeth Heeg-Truesdell, Carole LaBonne*

*Corresponding author for this work

Research output: Contribution to journalShort survey

7 Scopus citations

Abstract

The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.

Original languageEnglish (US)
Pages (from-to)R62-R64
JournalCurrent Biology
Volume16
Issue number2
DOIs
StatePublished - Jan 24 2006

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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