The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)