Wnt signaling: A shaggy dogma tale

Elizabeth Heeg-Truesdell; Carole LaBonne

doi:10.1016/j.cub.2006.01.004

Wnt signaling: A shaggy dogma tale

Elizabeth Heeg-Truesdell, Carole LaBonne^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.

Original language	English (US)
Pages (from-to)	R62-R64
Journal	Current Biology
Volume	16
Issue number	2
DOIs	https://doi.org/10.1016/j.cub.2006.01.004
State	Published - Jan 24 2006

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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@article{2f3a226167db489b87c8dba027a65e4e,

title = "Wnt signaling: A shaggy dogma tale",

abstract = "The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.",

author = "Elizabeth Heeg-Truesdell and Carole LaBonne",

year = "2006",

month = jan,

day = "24",

doi = "10.1016/j.cub.2006.01.004",

language = "English (US)",

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journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "2",

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TY - JOUR

T1 - Wnt signaling

T2 - A shaggy dogma tale

AU - Heeg-Truesdell, Elizabeth

AU - LaBonne, Carole

PY - 2006/1/24

Y1 - 2006/1/24

N2 - The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.

AB - The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.

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DO - 10.1016/j.cub.2006.01.004

M3 - Short survey

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SN - 0960-9822

VL - 16

SP - R62-R64

JO - Current Biology

JF - Current Biology

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Wnt signaling: A shaggy dogma tale

Abstract

ASJC Scopus subject areas

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