Wnt signaling

A shaggy dogma tale

Elizabeth Heeg-Truesdell, Carole LaBonne*

*Corresponding author for this work

Research output: Contribution to journalShort survey

7 Citations (Scopus)

Abstract

The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.

Original languageEnglish (US)
JournalCurrent Biology
Volume16
Issue number2
DOIs
StatePublished - Jan 24 2006

Fingerprint

Catenins
Protein-Serine-Threonine Kinases
phosphotransferases (kinases)
Phosphotransferases
threonine
serine
cells

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Heeg-Truesdell, Elizabeth ; LaBonne, Carole. / Wnt signaling : A shaggy dogma tale. In: Current Biology. 2006 ; Vol. 16, No. 2.
@article{2f3a226167db489b87c8dba027a65e4e,
title = "Wnt signaling: A shaggy dogma tale",
abstract = "The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.",
author = "Elizabeth Heeg-Truesdell and Carole LaBonne",
year = "2006",
month = "1",
day = "24",
doi = "10.1016/j.cub.2006.01.004",
language = "English (US)",
volume = "16",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Cell Press",
number = "2",

}

Wnt signaling : A shaggy dogma tale. / Heeg-Truesdell, Elizabeth; LaBonne, Carole.

In: Current Biology, Vol. 16, No. 2, 24.01.2006.

Research output: Contribution to journalShort survey

TY - JOUR

T1 - Wnt signaling

T2 - A shaggy dogma tale

AU - Heeg-Truesdell, Elizabeth

AU - LaBonne, Carole

PY - 2006/1/24

Y1 - 2006/1/24

N2 - The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.

AB - The serine/threonine kinase GSK3 is known to negatively regulate Wnt/β-catenin signaling, keeping downstream targets off in unstimulated cells. New studies have now unveiled an additional, positive role for GSK3 in Wnt signaling, as well as a new role for a second kinase, CK1γ.

UR - http://www.scopus.com/inward/record.url?scp=30944453237&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=30944453237&partnerID=8YFLogxK

U2 - 10.1016/j.cub.2006.01.004

DO - 10.1016/j.cub.2006.01.004

M3 - Short survey

VL - 16

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 2

ER -