Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites: The Corpus Christi Heart Project, 1988-1990

Harald Herholz; David C. Goff; David J. Ramsey; Frances A. Chan; Carmen Ortiz; Darwin R. Labarthe; Milton Z. Nichaman

doi:10.1016/0895-4356(95)00572-2

Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites: The Corpus Christi Heart Project, 1988-1990

Harald Herholz, David C. Goff^*, David J. Ramsey, Frances A. Chan, Carmen Ortiz, Darwin R. Labarthe, Milton Z. Nichaman

^*Corresponding author for this work

Preventive Medicine

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42 Scopus citations

Abstract

Mortality following myocardial infarction (MI) is greater among women than men and among Mexican Americans than non Hispanic whites. Because therapy can affect mortality following MI, we examined differences in discharge therapy among these groups. Data regarding discharge therapy of 982 patients in the Corpus Christi Heart Project showed that women received fewer cardiovascular drugs than men, and Mexican Americans received fewer cardiovascular drugs than non-Hispanic whites. In multivariate analysis adjusting for age, cigarettes smoking, diabetes, hypertension, congestive heart failure, and serum cholesterol, the odds ratio for receipt of cardiovascular medications was 0.51 (95% CI: 0.28-0.93) for women versus men and 0.62 (0.3-1.15) for Mexican Americans versus non Hispanic whites. Beta blockers were prescribed rarely. Thus, treatment differences between ethnic and gender groups were observed following MI. Further research is needed to determine both the reasons for these differences and the extent to which these differences contribute to the observed survival patterns following MI.

Original language	English (US)
Pages (from-to)	279-287
Number of pages	9
Journal	Journal of Clinical Epidemiology
Volume	49
Issue number	3
DOIs	https://doi.org/10.1016/0895-4356(95)00572-2
State	Published - Mar 1996

Funding

This investigation was supported by Grant Number HL38429, awarded by the National Heart. Lung, and Blood Institute, and b a grant awarded by the German Academic Exchange Service (DAAD), Bonn. Germany. The authors thank the Corpus Christi Advisory Committee, the Administrators and staffs of the participating hospitals, and the Corpus Christi-Nueces County Department of Public Health for their support of this project.

Keywords

Epidemiology
Ethnicity
Gender
Hispanic
Myocardial infarction
Treatment

ASJC Scopus subject areas

Epidemiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0895-4356(95)00572-2

Cite this

Herholz, H., Goff, D. C., Ramsey, D. J., Chan, F. A., Ortiz, C., Labarthe, D. R., & Nichaman, M. Z. (1996). Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites: The Corpus Christi Heart Project, 1988-1990. Journal of Clinical Epidemiology, 49(3), 279-287. https://doi.org/10.1016/0895-4356(95)00572-2

@article{1140e69fc04c4c3589e9429a1487b169,

title = "Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites: The Corpus Christi Heart Project, 1988-1990",

abstract = "Mortality following myocardial infarction (MI) is greater among women than men and among Mexican Americans than non Hispanic whites. Because therapy can affect mortality following MI, we examined differences in discharge therapy among these groups. Data regarding discharge therapy of 982 patients in the Corpus Christi Heart Project showed that women received fewer cardiovascular drugs than men, and Mexican Americans received fewer cardiovascular drugs than non-Hispanic whites. In multivariate analysis adjusting for age, cigarettes smoking, diabetes, hypertension, congestive heart failure, and serum cholesterol, the odds ratio for receipt of cardiovascular medications was 0.51 (95% CI: 0.28-0.93) for women versus men and 0.62 (0.3-1.15) for Mexican Americans versus non Hispanic whites. Beta blockers were prescribed rarely. Thus, treatment differences between ethnic and gender groups were observed following MI. Further research is needed to determine both the reasons for these differences and the extent to which these differences contribute to the observed survival patterns following MI.",

keywords = "Epidemiology, Ethnicity, Gender, Hispanic, Myocardial infarction, Treatment",

author = "Harald Herholz and Goff, {David C.} and Ramsey, {David J.} and Chan, {Frances A.} and Carmen Ortiz and Labarthe, {Darwin R.} and Nichaman, {Milton Z.}",

note = "Funding Information: We thank Drs Vishva Dixit (Genentech), James Olson (Fred Hutchinson Cancer Research Center), Eva Anton (UNC) for generously sharing ASC−/−, ND2:SmoA1 and hGFAP-cre mice, respectively. We appreciate the technical assistance provided by Vivian Xu, Michael Conlin and Meera Patel in the Deshmukh Lab; Janice Weaver, Lily Wai and Yongjuan Xia in the UNC Histopathology Core; Terese Camp and Ling Li in the UNC Genomics Core; Mark Vincent Olorvida, Stephanie Cohen and Bentley Midkiff in the UNC Translational Pathology Laboratory (TPL); and Joel Parker, George Wu, Chandri Yandava and Chris Fan at UNC for bioinformatics and biostatistics guidance. The UNC TPL is supported in part by grants from the National Cancer Institute (3P30CA016086) and the UNC University Cancer Research Fund. We would like to thank members of the Deshmukh Laboratory for critical review of this manuscript. TRG is supported by NIH Grant 1K08NS077978 and St Baldrick{\textquoteright}s Foundation. This work was supported by Grants NS042197 and GM078366 to MD.",

year = "1996",

month = mar,

doi = "10.1016/0895-4356(95)00572-2",

language = "English (US)",

volume = "49",

pages = "279--287",

journal = "Journal of Clinical Epidemiology",

issn = "0895-4356",

publisher = "Elsevier Inc.",

number = "3",

}

Herholz, H, Goff, DC, Ramsey, DJ, Chan, FA, Ortiz, C, Labarthe, DR & Nichaman, MZ 1996, 'Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites: The Corpus Christi Heart Project, 1988-1990', Journal of Clinical Epidemiology, vol. 49, no. 3, pp. 279-287. https://doi.org/10.1016/0895-4356(95)00572-2

Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites: The Corpus Christi Heart Project, 1988-1990. / Herholz, Harald; Goff, David C.; Ramsey, David J. et al.
In: Journal of Clinical Epidemiology, Vol. 49, No. 3, 03.1996, p. 279-287.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites

T2 - The Corpus Christi Heart Project, 1988-1990

AU - Herholz, Harald

AU - Goff, David C.

AU - Ramsey, David J.

AU - Chan, Frances A.

AU - Ortiz, Carmen

AU - Labarthe, Darwin R.

AU - Nichaman, Milton Z.

N1 - Funding Information: We thank Drs Vishva Dixit (Genentech), James Olson (Fred Hutchinson Cancer Research Center), Eva Anton (UNC) for generously sharing ASC−/−, ND2:SmoA1 and hGFAP-cre mice, respectively. We appreciate the technical assistance provided by Vivian Xu, Michael Conlin and Meera Patel in the Deshmukh Lab; Janice Weaver, Lily Wai and Yongjuan Xia in the UNC Histopathology Core; Terese Camp and Ling Li in the UNC Genomics Core; Mark Vincent Olorvida, Stephanie Cohen and Bentley Midkiff in the UNC Translational Pathology Laboratory (TPL); and Joel Parker, George Wu, Chandri Yandava and Chris Fan at UNC for bioinformatics and biostatistics guidance. The UNC TPL is supported in part by grants from the National Cancer Institute (3P30CA016086) and the UNC University Cancer Research Fund. We would like to thank members of the Deshmukh Laboratory for critical review of this manuscript. TRG is supported by NIH Grant 1K08NS077978 and St Baldrick’s Foundation. This work was supported by Grants NS042197 and GM078366 to MD.

PY - 1996/3

Y1 - 1996/3

N2 - Mortality following myocardial infarction (MI) is greater among women than men and among Mexican Americans than non Hispanic whites. Because therapy can affect mortality following MI, we examined differences in discharge therapy among these groups. Data regarding discharge therapy of 982 patients in the Corpus Christi Heart Project showed that women received fewer cardiovascular drugs than men, and Mexican Americans received fewer cardiovascular drugs than non-Hispanic whites. In multivariate analysis adjusting for age, cigarettes smoking, diabetes, hypertension, congestive heart failure, and serum cholesterol, the odds ratio for receipt of cardiovascular medications was 0.51 (95% CI: 0.28-0.93) for women versus men and 0.62 (0.3-1.15) for Mexican Americans versus non Hispanic whites. Beta blockers were prescribed rarely. Thus, treatment differences between ethnic and gender groups were observed following MI. Further research is needed to determine both the reasons for these differences and the extent to which these differences contribute to the observed survival patterns following MI.

AB - Mortality following myocardial infarction (MI) is greater among women than men and among Mexican Americans than non Hispanic whites. Because therapy can affect mortality following MI, we examined differences in discharge therapy among these groups. Data regarding discharge therapy of 982 patients in the Corpus Christi Heart Project showed that women received fewer cardiovascular drugs than men, and Mexican Americans received fewer cardiovascular drugs than non-Hispanic whites. In multivariate analysis adjusting for age, cigarettes smoking, diabetes, hypertension, congestive heart failure, and serum cholesterol, the odds ratio for receipt of cardiovascular medications was 0.51 (95% CI: 0.28-0.93) for women versus men and 0.62 (0.3-1.15) for Mexican Americans versus non Hispanic whites. Beta blockers were prescribed rarely. Thus, treatment differences between ethnic and gender groups were observed following MI. Further research is needed to determine both the reasons for these differences and the extent to which these differences contribute to the observed survival patterns following MI.

KW - Epidemiology

KW - Ethnicity

KW - Gender

KW - Hispanic

KW - Myocardial infarction

KW - Treatment

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UR - http://www.scopus.com/inward/citedby.url?scp=0029914282&partnerID=8YFLogxK

U2 - 10.1016/0895-4356(95)00572-2

DO - 10.1016/0895-4356(95)00572-2

M3 - Article

C2 - 8676174

AN - SCOPUS:0029914282

SN - 0895-4356

VL - 49

SP - 279

EP - 287

JO - Journal of Clinical Epidemiology

JF - Journal of Clinical Epidemiology

IS - 3

ER -

Women and Mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-Hispanic whites: The Corpus Christi Heart Project, 1988-1990

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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