Abnormalities of ventilatory regulation may arise from primary disease of the central respiratory centers and peripheral chemoreceptors or from an inability of an abnormal ventilatory apparatus to respond normally to appropriate stimuli. The precise basis of abnormal regulation of ventilation in disease is obscured further by interactions between nervous regulatory centers and the consequences of chronic abnormalities in blood gas composition and acid-base status. These secondary effects themselves are also capable of altering the functional state of the nervous regulatory centers.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Review of Respiratory Disease|
|State||Published - Nov 29 1977|
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine