Wyburn-Mason Syndrome Associated with Cutaneous Reactive Angiomatosis and Central Retinal Vein Occlusion

Alison B. Callahan, Dimitra Skondra, Magdalena Krzystolik, Yoshihiro Yonekawa, Dean Eliott*

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Retinal venous occlusive events are a rare complication of arteriovenous malformations of the retina found in Wyburn-Mason syndrome. The authors present a case of a 28-year-old man diagnosed with Wyburn-Mason syndrome and cutaneous reactive angiomatosis, a reactive angioproliferative disorder induced by vascular occlusion. He developed a central retinal vein occlusion complicated by macular edema and received treatment with intravitreal bevacizumab, which led to resolution of the edema. To the best of the authors' knowledge, this is the first report of an anti-vascular endothelial growth factor agent employed as an effective treatment for macular edema in the setting of Wyburn-Mason syndrome. The association between Wyburn-Mason syndrome and cutaneous reactive angiomatosis is also a novel finding.

Original languageEnglish (US)
Pages (from-to)760-762
Number of pages3
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume46
Issue number7
DOIs
StatePublished - Jul 1 2015

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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