Xerostomia: 12-Month changes in saliva production and its relationship to perception and performance of swallow function, oral intake, and diet after chemoradiation

Jeri A. Logemann*, Barbara Roa Pauloski, Alfred W. Rademaker, Cathy L. Lazarus, Bharat Mittal, Joy Gaziano, Linda Stachowiak, Ellen MacCracken, Lisa A. Newman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

118 Scopus citations

Abstract

Background. Previous investigators have found permanent changes in saliva production after chemoradiation but have not examined these in relation to swallowing measures, diet changes, and patient comfort over time. Methods. Thirty patients with advanced stage cancer of the oropharynx treated with chemoradiation were followed with videofluoroscopic swallow studies, a measure of stimulated total saliva production, a questionnaire of their perception of dry mouth, and a questionnaire on the nature of their oral intake at pretreatment until 12 months after treatment. Results. Saliva declined significantly from pretreatment to 12 months. Swallowing-related complaints increased significantly over the 12 months, especially in patients with lower saliva weights. Diet choices increased over time after treatment, except crunchy foods. Swallow measures did not relate to saliva weight. Conclusions. Reduced saliva weight does not correlate with slowed or inefficient swallow. Instead, reduced saliva weight seems to change patients' perceptions of their swallowing ability and, on that basis, their diet choices.

Original languageEnglish (US)
Pages (from-to)432-437
Number of pages6
JournalHead and Neck
Volume25
Issue number6
DOIs
StatePublished - Jun 1 2003

Keywords

  • Chemoradiation
  • Diet
  • Swallowing
  • Videofluoroscopy
  • Xerostomia

ASJC Scopus subject areas

  • Otorhinolaryngology

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