Purpose: To compare various computed tomography (CT) parameters to the positron emission tomography with computed tomography (PET-CT) response, with or without PET guidance for the response assessment of colorectal cancer (CRC) metastases treated by Y90 radioembolization. Methods: Thirty-six CRC metastases were retrospectively evaluated on 18F-Fluoro-Deoxy-Glucose PET-CT and contrast-enhanced computed tomography (CECT) performed at baseline and 2-3 months after Y90 radioembolization. Results: Median SUVmax values decreased from 11.39 to 6.71 after radioembolization (P< .001), and 23/36 (64%) metastases were categorized metabolic responses according to European Organisation for Research and Treatment of Cancer criteria. Only a decrease of the mean attenuation in the structural (P< .001) and metabolic active volume (P< .001) was observed. The change in these criteria was correlated with the change of SUVmax.
- Colorectal cancer
- Liver metastases
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging