Zolpidem en la enfermedad de Parkinson

Translated title of the contribution: Zolpiden in Parkinson's disease

Luz Abaroa*, Leo Verhagen Metman, Tomoko Arakaki, Maximiliano R. Arce, Nelida S. Garretto

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction Zolpidem is a non-benzodiazepine GABA-modulator that may provide benefit in various movement disorders. Clinical cases We report 5 patients with Parkinson's disease who experienced significant improvement in motor and non-motor symptoms following treatment with this drug. In addition we observed improvements in levodopa-associated motor complications and discuss the possible mechanism of action. Conclusion Modulators of the GABAergic system, such as zolpidem, may offer an alternative therapeutic approach for patients with Parkinson's disease. Further studies are needed to determine the benefits and risks of using this class of drugs in Parkinson's disease and other movement disorders.

Translated title of the contributionZolpiden in Parkinson's disease
Original languageSpanish
Pages (from-to)230-233
Number of pages4
JournalNeurologia Argentina
Volume6
Issue number4
DOIs
StatePublished - Oct 1 2014

Keywords

  • Motor and non-motor symptoms
  • Parkinson's disease
  • Zolpidem

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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